Hair Loss (Dutasteride (Avodart))
What is dutasteride?
Anabolic-androgenic steroid use by bodybuilders can hasten the loss of scalp hair. The body's increased testosterone hormone levels are to blame for this. The body converts more testosterone into DHT, the more of it there is. Running DHT derivatives like Masteron, Winstrol, or Proviron will also raise DHT levels.
Androgenetic alopecia (hair loss on the head) and hirsutism (body hair in women) are caused by an increase in the hormone dihydrotestosterone in men after using androgenic steroids. Bodybuilders have tried 5a-reductase inhibitors like dutasteride (also known by the brand name Avodart) to protect their existing hair and even re-grow more to combat this.
How does dutasteride (Avodart) reduce hair loss?
We must first learn about DHT to comprehend how Avodart functions. Dihydrotestosterone (DHT) is an androgen hormone and a sex steroid. The testicles, hair follicles, adrenal glands, and prostate all produce DHT thanks to the enzyme 5a-reductase. By preventing the action of the enzymes that turn testosterone into DHT, reductase inhibitors’ function. This explains why they are so effective at preventing hair loss, promoting hair growth, and treating BPH. DHT levels can be reduced by up to 95% when dutasteride and finasteride are combined.
The name of the drug—dual-tasteride—distinguishes it from finasteride because it affects both 5a-reductase enzymes, whereas finasteride only affects one. Because of this, dutasteride has higher efficacy and is more effective at lower doses.
The beneficial effects of dutasteride
- Male-pattern hair loss and the emergence of benign prostatic hyperplasia are two conditions of DHT that affects men.
- Dutasteride differs from the first-generation reductase inhibitor in its tissue selectivity even though it shares similarities with finasteride in terms of structure and mode of action.
- As a result, it prevents the conversion of DHT in all tissues, including the skin, prostate, liver, and scalp.
- As a result, it significantly reduces systemic DHT levels more effectively than finasteride.
Application and dosage of dutasteride
Bodybuilders frequently start with a daily dose of 2.5 mg. Most guys split the dose into AM and PM, but this is not necessary. Dutasteride has a very long half-life, up to 5 weeks. Therefore, you are free to dose it EOD (every other day) or longer if you so choose.
Potential side effects of Avodart
In the long run, it might not be the best idea to stop testosterone from being converted into the sex hormone DHT. Avodart might not be for you if you value your sex drive. The following are a few side effects of this medication:
- Erection problems
- Reduced sexual arousal
- Pronounced drops in DHT levels
Some users have reported serious erectile dysfunction problems even with brief use at low dosages. As a result, when using Duta, the user must exercise extreme caution and only do so when necessary.
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