Anti Estrogens (Letrozole)
What is letrozole?
Letrozole, also referred to by the brand name Femara, is an anti-estrogen that is a member of the drug class and subcategory known as aromatase inhibitors (AIs). It is one of the three available non-steroidal AIs. It was created after exemestane (Aromasin) but before anastrozole (Arimidex). It has the longest duration of action (on average, more than 40 hours) and is the strongest and most effective AI of the three.
The use of Femara by bodybuilders and athletes
Letrozole's use among athletes and bodybuilders spread quickly due to the drug's outstanding qualities. When using anabolic steroids, people typically prefer aromatase inhibitors like Letrozole because they can stop the aromatization process, which causes rising estrogen levels, and avoid side effects like gynecomastia or water retention as a result.
Application and dosage of Femara
Doses of letrozole range from 1.25 mg to 2.5 mg per day. As each person should gradually adjust their dose based on how they feel and how their body is responding, the dosage is flexible and it becomes a matter of personal preference. For some anabolic steroid users, even 1.25mg per day is too much. Occasionally, the recommended dose is 1.25mg every other day, and frequently, this can be even less frequently, especially given that letrozole's half-life is 2-4 days.
Potential side effects from letrozole
The following are some possible side effects of letrozole use:
- Hot flushes
- Balding hair
- General weakness
- Localized swelling
- Moderate to severe rashes
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